Why does adrenal insufficiency cause hypercalcemia

Declaration of interest: There is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported. Funding: No specific grant from any funding agency in the public, commercial or not-for-profit sector. Browse other volumes. Biosci Abstracts Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Searchable abstracts of presentations at key conferences in endocrinology. Endocrine Abstracts. Prev Next. Endocrine Abstracts 28 P Author affiliations. Adrenal insufficiency should be considered in the differential of PTH-independent hypercalcemia. This case highlights the improvement in hypercalcemia that is seen with correction of glucocorticoid deficiency, and supports delaying additional work up for other PTH-independent causes until appropriate treatment has been given.

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Volume 5. Article Contents Abstract. The prevalence of hypercalcemia due to adrenal insufficiency was 1. The causes of adrenal insufficiency were isolated ACTH deficiency, pituitary apoplexy, pituitary atrophy, glucocorticoid withdrawal syndrome, and unilateral adrenalectomy. Serum calcium Ca levels corrected by serum albumin were maximally increased to Single CRH injections failed to increase serum cortisol in any of the patients.

Glucocorticoid replacement acutely normalized serum Ca and decreased levels of carboxy-terminal telopeptide of type I collagen, a marker of bone resorption.

Conclusion Adrenal insufficiency could therefore be an occult cause of hypercalcemia in anuric HD patients who are critically ill. Japanese Journal of Medicine. Already have an account?

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